Hepatitis B therapy: The plot thickens

Glatiramer acetate therapy: the plot thickens.

G LATIRAMER ACETATE (COPAXONE; TEVA Pharmaceuticals, North Wales, Pa) is a random polymer of glutamic acid, lysine, alanine, and tyrosine, and is of considerable interest for its ability to reduce the frequency of relapses in relapsing-remitting multiple sclerosis (MS). Several mechanisms have been proposed to explain these findings. Lando et al suggested that inhibition of clinical disease in ...

MACHOs: THE PLOT THICKENS

We discuss the implications of the recent upward revision of the LMC microlensing rate by the MACHO Collaboration. We conclude: (i) A good case for the existence of baryonic dark matter in the halo has been made; (ii) The case for the existence of cold dark matter is unaffected and still compelling; and (iii) The Galactic halo is still an excellent place to search for cold dark matter particles...

The plot thickens.

The dilator function of the vascular endothelium is critical for optimal tissue perfusion, and this is brought into stark reality in a number of diseases, such as hypertension, diabetes, and preeclampsia, in which endothelium-dependent vasodilator function is impaired. Prostacyclin and nitric oxide (NO) were the earliest identified endothelium-dependent vasodilators, but it was soon found that ...

Paul Wellstone : The Plot Thickens

In response to my analysis of the Wellstone tragedy (READER WEEKLY, 28 November 2002, pp. 18-19) and related discussion of this event, I have received quite a few emails, many of which have taken strong exception to the very idea that George W. Bush could ever have been involved in something of this kind. My suggestion that Republicans may have been motivated to take Wellstone out, alas, is not...

Peginterferon maintenance therapy in patients with advanced hepatitis C to prevent hepatocellular carcinoma: the plot thickens.